Features of the immune response of rainbow trout to vaccination of antigens Yersinia ruckeri, Aeromonas salmonicida, Listonella anguillarum and Renibacterium salmoninarum

The antigens of Yersinia ruckeri, Aeromonas salmonicida sp.salmonicida, Listonella anguillarum and Renibacterium salmoninarum were immunized to rainbow trout different ages immersion intraperitaneal, then waited 300 degree days, after which they infected with homologous heterologous strains the studied microorganisms. Prepared their various combinations used in experiments. After control infection, level protective immunity was compared. antibacterial protection obtained by introduction polyvalent variants comparable that acquired from monovalent antigens. A number cross–reactions detected - so vaccination pure A. antigen provided some against infection L. Y. ruckeri. In addition, addition R. combination enhanced effect other diseases a greater extent than infection.